Created and operated by its physician members, the Canadian ALS Research Network (CALS) is a national alliance of leading ALS clinicians and researchers committed to the expansion of ALS clinical research studies in Canada and to the pursuit of effective therapies for patients with ALS.
This includes both investigator and industry initiated multicentre national and international studies testing promising therapeutics for patients with ALS. CALS is a non-profit, non-share corporation which is supported by the ALS Society of Canada and is a recognized affiliate society of the Canadian Neurological Sciences Federation (CNSF). CALS has a cooperative relationship with the Northeast ALS Consortium (NEALS) in the United States and the two networks have collaborated in a number of NIH, ALS Society of Canada and ALS Association funded clinical trials.
In addition to investigator initiated studies, CALS pursues clinical trials in partnership with pharmaceutical industry (see details below). In this way, the CALS Network can attract the most promising therapeutics for Canadian patients with ALS and continue to be on the cutting edge of the medical research field. In cooperation with industry, CALS collectively offers national access to key patient groups, clinical-research expertise and best practice methodology, in a mutual quest to bring better treatments to market efficiently and effectively for patients with ALS.
With numerous ALS research centres of excellence across Canada, CALS facilitates collaborative research initiatives that cannot be achieved by a single centre. CALS sites provide a multidisciplinary approach to the care of patients with ALS and their families. With a universal health care system in Canada, the vast majority of ALS patients with ALS are followed in CALS clinics and the majority of patients are keen to participate in clinical trials. With well established research infrastructure including ALS outcomes measure certification and experience in International ALS clinical trial, CALS can rapidly and efficiently accrue subjects for clinical studies.
The CALS Network creates value by:
- Providing a disease-specific focus and concentration of expertise.
- Partnering with other national ALS Research networks or with industry to find meaningful treatments for patients with ALS.
- Building and managing national resources to facilitate clinical research studies and optimize clinical care.
- Providing an efficient professional business approach based on fairness, transparency and credibility.
- Setting standards for clinical research and clinical trial performance.